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Effects of substrate binding site residue substitutions of xynA from Bacillus amyloliquefaciens on substrate specificity

BACKGROUND: The aromatic residues of xylanase enzyme, W187, Y124, W144, Y128 and W63 of substrate binding pocket from Bacillus amyloliquefaciens were investigated for their role in substrate binding by homology modelling and sequence analysis. These residues are highly conserved and play an importan...

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Detalles Bibliográficos
Autores principales: Prajapati, Anil S., Pawar, Vishakha A., Panchal, Ketankumar J., Sudhir, Ankit P., Dave, Bhaumik R., Patel, Darshan H., Subramanian, R. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812043/
https://www.ncbi.nlm.nih.gov/pubmed/29439688
http://dx.doi.org/10.1186/s12896-018-0420-7