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One-step grafting of temperature-and pH-sensitive (N-vinylcaprolactam-co-4-vinylpyridine) onto silicone rubber for drug delivery

A one-step method was implemented to graft N-vinylcaprolactam (NVCL) and 4-vinylpyridine (4VP) onto silicone rubber (SR) films using gamma radiation in order to endow the silicone surface with temperature- and pH-responsiveness, and give it the ability to host and release diclofenac in a controlled...

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Detalles Bibliográficos
Autores principales: Pino-Ramos, Victor H., Alvarez-Lorenzo, Carmen, Concheiro, Angel, Bucio, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812122/
https://www.ncbi.nlm.nih.gov/pubmed/29491777
http://dx.doi.org/10.1080/15685551.2016.1231033