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Phase I study of an active immunotherapy for asymptomatic phase Lymphoplasmacytic lymphoma with DNA vaccines encoding antigen-chemokine fusion: study protocol

BACKGROUND: There is now a renewed interest in cancer vaccines. Patients responding to immune checkpoint blockade usually bear tumors that are heavily infiltrated by T cells and express a high load of neoantigens, indicating that the immune system is involved in the therapeutic effect of these agent...

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Detalles Bibliográficos
Autores principales: Thomas, Sheeba K., Cha, Soung-chul, Smith, D. Lynne, Kim, Kun Hwa, Parshottam, Sapna R., Rao, Sheetal, Popescu, Michael, Lee, Vincent Y., Neelapu, Sattva S., Kwak, Larry W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812202/
https://www.ncbi.nlm.nih.gov/pubmed/29439670
http://dx.doi.org/10.1186/s12885-018-4094-2