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TFAP2C promotes stemness and chemotherapeutic resistance in colorectal cancer via inactivating hippo signaling pathway

BACKGROUND: Aberrant expression of transcription Factor AP-2 Gamma (TFAP2C) has been reported to be implicated in malignant process of many cancers. The purpose of this study is to investigate the clinical significance and biological roles of TFAP2C in colorectal cancer (CRC). METHODS: TFAP2C expres...

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Detalles Bibliográficos
Autores principales: Wang, Xu, Sun, Di, Tai, Jiandong, Chen, Si, Yu, Miao, Ren, Dong, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812206/
https://www.ncbi.nlm.nih.gov/pubmed/29439714
http://dx.doi.org/10.1186/s13046-018-0683-9