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A novel CAV derived cell-penetrating peptide efficiently delivers exogenous molecules through caveolae-mediated endocytosis

Cell-penetrating peptide (CPP) is a promising cargo for delivering bioactive molecules. In this study, the N terminus of VP1 from chicken anemia virus, designated as CVP1, was found to carry enriched arginine residues with α-helix. By confocal imaging, flow cytometry and MTT assay, we identified CVP...

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Detalles Bibliográficos
Autores principales: Hu, Gaowei, Zheng, Wenlv, Li, Ao, Mu, Yaru, Shi, Mingyu, Li, Tuofan, Zou, Haitao, Shao, Hongxia, Qin, Aijian, Ye, Jianqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812233/
https://www.ncbi.nlm.nih.gov/pubmed/29439726
http://dx.doi.org/10.1186/s13567-018-0513-2