Genetically encoded calcium indicator with NTnC-like design and enhanced fluorescence contrast and kinetics

BACKGROUND: The recently developed genetically encoded calcium indicator (GECI), called NTnC, has a novel design with reduced size due to utilization of the troponin C (TnC) as a Ca(2+)-binding moiety inserted into the mNeonGreen fluorescent protein. NTnC binds two times less Ca(2+) ions while maint...

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Detalles Bibliográficos
Autores principales: Doronin, D. A., Barykina, N. V., Subach, O. M., Sotskov, V. P., Plusnin, V. V., Ivleva, O. A., Isaakova, E. A., Varizhuk, A. M., Pozmogova, G. E., Malyshev, A. Y., Smirnov, I. V., Piatkevich, K. D., Anokhin, K. V., Enikolopov, G. N., Subach, F. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812234/
https://www.ncbi.nlm.nih.gov/pubmed/29439686
http://dx.doi.org/10.1186/s12896-018-0417-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812234/
https://www.ncbi.nlm.nih.gov/pubmed/29439686
http://dx.doi.org/10.1186/s12896-018-0417-2

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