Circulating cell-free plasma tumour DNA shows a higher incidence of EGFR mutations in patients with extrathoracic disease progression

BACKGROUND: Non-invasive monitoring of epidermal growth factor receptor (EGFR) mutations conferring sensitivity and resistance to tyrosine kinase inhibitors (TKIs) is vital for efficient therapy of lung adenocarcinoma (LADC). Although plasma circulating cell-free tumour DNA (ctDNA) is detectable at...

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Detalles Bibliográficos
Autores principales: Seki, Yoshitaka, Fujiwara, Yutaka, Kohno, Takashi, Yoshida, Kazushi, Goto, Yasushi, Horinouchi, Hidehito, Kanda, Shintaro, Nokihara, Hiroshi, Yamamoto, Noboru, Kuwano, Kazuyoshi, Ohe, Yuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812398/
https://www.ncbi.nlm.nih.gov/pubmed/29464111
http://dx.doi.org/10.1136/esmoopen-2017-000292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812398/
https://www.ncbi.nlm.nih.gov/pubmed/29464111
http://dx.doi.org/10.1136/esmoopen-2017-000292

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