An ancestral TMEM16 homolog from Dictyostelium discoideum forms a scramblase

TMEM16 proteins are a recently identified protein family comprising Ca(2+)-activated Cl(-) channels that generate outwardly rectifying ionic currents in response to intracellular Ca(2+) elevations. Some TMEM16 family members, such as TMEM16F/ANO6 are also essential for Ca(2+)-dependent phospholipid...

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Detalles Bibliográficos
Autores principales: Pelz, Thomas, Drose, Daniela R., Fleck, David, Henkel, Bastian, Ackels, Tobias, Spehr, Marc, Neuhaus, Eva M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812556/
https://www.ncbi.nlm.nih.gov/pubmed/29444117
http://dx.doi.org/10.1371/journal.pone.0191219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812556/
https://www.ncbi.nlm.nih.gov/pubmed/29444117
http://dx.doi.org/10.1371/journal.pone.0191219

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