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An ancestral TMEM16 homolog from Dictyostelium discoideum forms a scramblase
TMEM16 proteins are a recently identified protein family comprising Ca(2+)-activated Cl(-) channels that generate outwardly rectifying ionic currents in response to intracellular Ca(2+) elevations. Some TMEM16 family members, such as TMEM16F/ANO6 are also essential for Ca(2+)-dependent phospholipid...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812556/ https://www.ncbi.nlm.nih.gov/pubmed/29444117 http://dx.doi.org/10.1371/journal.pone.0191219 |