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S100B as an antagonist to block the interaction between S100A1 and the RAGE V domain

Ca2(+)-binding human S100A1 protein is a type of S100 protein. S100A1 is a significant mediator during inflammation when Ca(2+) binds to its EF-hand motifs. Receptors for advanced glycation end products (RAGE) correspond to 5 domains: the cytoplasmic, transmembrane, C2, C1, and V domains. The V doma...

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Detalles Bibliográficos
Autores principales: Khan, Md. Imran, Su, Yu-Kai, Zou, Jinhao, Yang, Lee-Wei, Chou, Ruey-Hwang, Yu, Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812564/
https://www.ncbi.nlm.nih.gov/pubmed/29444082
http://dx.doi.org/10.1371/journal.pone.0190545