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S100B as an antagonist to block the interaction between S100A1 and the RAGE V domain
Ca2(+)-binding human S100A1 protein is a type of S100 protein. S100A1 is a significant mediator during inflammation when Ca(2+) binds to its EF-hand motifs. Receptors for advanced glycation end products (RAGE) correspond to 5 domains: the cytoplasmic, transmembrane, C2, C1, and V domains. The V doma...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812564/ https://www.ncbi.nlm.nih.gov/pubmed/29444082 http://dx.doi.org/10.1371/journal.pone.0190545 |