Effects of protein-protein interactions and ligand binding on the ion permeation in KCNQ1 potassium channel

The voltage-gated KCNQ1 potassium ion channel interacts with the type I transmembrane protein minK (KCNE1) to generate the slow delayed rectifier (I(Ks)) current in the heart. Mutations in these transmembrane proteins have been linked with several heart-related issues, including long QT syndromes (L...

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Detalles Bibliográficos
Autores principales: Jalily Hasani, Horia, Ganesan, Aravindhan, Ahmed, Marawan, Barakat, Khaled H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812580/
https://www.ncbi.nlm.nih.gov/pubmed/29444113
http://dx.doi.org/10.1371/journal.pone.0191905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812580/
https://www.ncbi.nlm.nih.gov/pubmed/29444113
http://dx.doi.org/10.1371/journal.pone.0191905

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