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Effects of protein-protein interactions and ligand binding on the ion permeation in KCNQ1 potassium channel
The voltage-gated KCNQ1 potassium ion channel interacts with the type I transmembrane protein minK (KCNE1) to generate the slow delayed rectifier (I(Ks)) current in the heart. Mutations in these transmembrane proteins have been linked with several heart-related issues, including long QT syndromes (L...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812580/ https://www.ncbi.nlm.nih.gov/pubmed/29444113 http://dx.doi.org/10.1371/journal.pone.0191905 |