LY2405319, an analog of fibroblast growth factor 21 ameliorates α-smooth muscle actin production through inhibition of the succinate—G-protein couple receptor 91 (GPR91) pathway in mice

Fibroblast growth factor 21 (FGF21) is an important metabolic regulator expressed predominantly in the liver. In this study, we evaluated the role of LY2405319, an analogue of FGF21, in hepatic stellate cell (HSC) activation and in a methionine and choline-deficient (MCD)-diet induced mouse model of...

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Detalles Bibliográficos
Autores principales: Le, Cong Thuc, Nguyen, Giang, Park, So Young, Choi, Dae Hee, Cho, Eun-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812602/
https://www.ncbi.nlm.nih.gov/pubmed/29444136
http://dx.doi.org/10.1371/journal.pone.0192146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812602/
https://www.ncbi.nlm.nih.gov/pubmed/29444136
http://dx.doi.org/10.1371/journal.pone.0192146

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