Cargando…
Antitumor effects of metformin via indirect inhibition of protein phosphatase 2A in patients with endometrial cancer
OBJECTIVE: Metformin, an antidiabetic drug, inhibits the endometrial cancer cell growth in vivo by improving the insulin resistance; however, its mechanism of action is not completely understood. Protein phosphatase 2A (PP2A) is a serine/threonine phosphatase associated with insulin resistance and t...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812621/ https://www.ncbi.nlm.nih.gov/pubmed/29444159 http://dx.doi.org/10.1371/journal.pone.0192759 |