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A long-term mechanistic computational model of physiological factors driving the onset of type 2 diabetes in an individual

A computational model of the physiological mechanisms driving an individual's health towards onset of type 2 diabetes (T2D) is described, calibrated and validated using data from the Diabetes Prevention Program (DPP). The objective of this model is to quantify the factors that can be used for p...

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Detalles Bibliográficos
Autores principales: Sarkar, Joydeep, Dwivedi, Gaurav, Chen, Qian, Sheu, Iris E., Paich, Mark, Chelini, Colleen M., D'Alessandro, Paul M., Burns, Samuel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812629/
https://www.ncbi.nlm.nih.gov/pubmed/29444133
http://dx.doi.org/10.1371/journal.pone.0192472