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Transcriptome variations among human embryonic stem cell lines are associated with their differentiation propensity

Human embryonic stem cells (hESCs) have the potential to form any cell type in the body, making them attractive cell sources in drug screening, regenerative medicine, disease and developmental processes modeling. However, not all hESC lines have the equal potency to generate desired cell types in vi...

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Detalles Bibliográficos
Autores principales: Sun, Changbin, Zhang, Jiawen, Zheng, Dongmin, Wang, Jian, Yang, Huanming, Zhang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812638/
https://www.ncbi.nlm.nih.gov/pubmed/29444173
http://dx.doi.org/10.1371/journal.pone.0192625