Protein S-glutathionylation lowers superoxide/hydrogen peroxide release from skeletal muscle mitochondria through modification of complex I and inhibition of pyruvate uptake

Protein S-glutathionylation is a reversible redox modification that regulates mitochondrial metabolism and reactive oxygen species (ROS) production in liver and cardiac tissue. However, whether or not it controls ROS release from skeletal muscle mitochondria has not been explored. In the present stu...

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Detalles Bibliográficos
Autores principales: Gill, Robert M., O’Brien, Marisa, Young, Adrian, Gardiner, Danielle, Mailloux, Ryan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812644/
https://www.ncbi.nlm.nih.gov/pubmed/29444156
http://dx.doi.org/10.1371/journal.pone.0192801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812644/
https://www.ncbi.nlm.nih.gov/pubmed/29444156
http://dx.doi.org/10.1371/journal.pone.0192801

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