Cargando…
Multiscale Kinetic Modeling Reveals an Ensemble of Cl(–)/H(+) Exchange Pathways in ClC-ec1 Antiporter
[Image: see text] Despite several years of research, the ion exchange mechanisms in chloride/proton antiporters and many other coupled transporters are not yet understood at the molecular level. Here, we present a novel approach to kinetic modeling and apply it to ion exchange in ClC-ec1. Our multis...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2018
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812667/ https://www.ncbi.nlm.nih.gov/pubmed/29332400 http://dx.doi.org/10.1021/jacs.7b11463 |