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MukB ATPases are regulated independently by the N- and C-terminal domains of MukF kleisin

The Escherichia coli SMC complex, MukBEF, acts in chromosome segregation. MukBEF shares the distinctive architecture of other SMC complexes, with one prominent difference; unlike other kleisins, MukF forms dimers through its N-terminal domain. We show that a 4-helix bundle adjacent to the MukF dimer...

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Detalles Bibliográficos
Autores principales: Zawadzka, Katarzyna, Zawadzki, Pawel, Baker, Rachel, Rajasekar, Karthik V, Wagner, Florence, Sherratt, David J, Arciszewska, Lidia K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812716/
https://www.ncbi.nlm.nih.gov/pubmed/29323635
http://dx.doi.org/10.7554/eLife.31522