NADPH oxidase mediates microtubule alterations and diaphragm dysfunction in dystrophic mice

Skeletal muscle from mdx mice is characterized by increased Nox2 ROS, altered microtubule network, increased muscle stiffness, and decreased muscle/respiratory function. While microtubule de-tyrosination has been suggested to increase stiffness and Nox2 ROS production in isolated single myofibers, i...

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Detalles Bibliográficos
Autores principales: Loehr, James Anthony, Wang, Shang, Cully, Tanya R, Pal, Rituraj, Larina, Irina V, Larin, Kirill V, Rodney, George G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812717/
https://www.ncbi.nlm.nih.gov/pubmed/29381135
http://dx.doi.org/10.7554/eLife.31732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812717/
https://www.ncbi.nlm.nih.gov/pubmed/29381135
http://dx.doi.org/10.7554/eLife.31732

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