Parental micronutrient deficiency distorts liver DNA methylation and expression of lipid genes associated with a fatty-liver-like phenotype in offspring

Micronutrient status of parents can affect long term health of their progeny. Around 2 billion humans are affected by chronic micronutrient deficiency. In this study we use zebrafish as a model system to examine morphological, molecular and epigenetic changes in mature offspring of parents that expe...

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Detalles Bibliográficos
Autores principales: Skjærven, Kaja H., Jakt, Lars Martin, Fernandes, Jorge M. O., Dahl, John Arne, Adam, Anne-Catrin, Klughammer, Johanna, Bock, Christoph, Espe, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812986/
https://www.ncbi.nlm.nih.gov/pubmed/29445184
http://dx.doi.org/10.1038/s41598-018-21211-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812986/
https://www.ncbi.nlm.nih.gov/pubmed/29445184
http://dx.doi.org/10.1038/s41598-018-21211-5

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