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Enhanced viral-mediated cochlear gene delivery in adult mice by combining canal fenestration with round window membrane inoculation
Cochlear gene therapy holds promise for the treatment of genetic deafness. Assessing its impact in adult murine models of hearing loss, however, has been hampered by technical challenges that have made it difficult to establish a robust method to deliver transgenes to the mature murine inner ear. He...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812997/ https://www.ncbi.nlm.nih.gov/pubmed/29445157 http://dx.doi.org/10.1038/s41598-018-21233-z |