Reversal of stress fibre formation by Nitric Oxide mediated RhoA inhibition leads to reduction in the height of preformed thrombi

Evidence has emerged to suggest that thrombi are dynamic structures with distinct areas of differing platelet activation and inhibition. We hypothesised that Nitric oxide (NO), a platelet inhibitor, can modulate the actin cytoskeleton reversing platelet spreading, and therefore reduce the capability...

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Detalles Bibliográficos
Autores principales: Atkinson, L., Yusuf, M. Z., Aburima, A., Ahmed, Y., Thomas, S. G., Naseem, K. M., Calaminus, S. D. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813033/
https://www.ncbi.nlm.nih.gov/pubmed/29445102
http://dx.doi.org/10.1038/s41598-018-21167-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813033/
https://www.ncbi.nlm.nih.gov/pubmed/29445102
http://dx.doi.org/10.1038/s41598-018-21167-6

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