Lack of T-bet reduces monocytic interleukin-12 formation and accelerates thrombus resolution in deep vein thrombosis

The role of leukocytes in deep vein thrombosis (DVT) resolution is incompletely understood. We determined how depletion of lysozyme positive (LysM(+)) cells and a switched-off type 1 immune response influences thrombus resolution. DVT was induced in 12-week-old male mice by inferior vena cava (IVC)...

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Detalles Bibliográficos
Autores principales: Schönfelder, Tanja, Brandt, Moritz, Kossmann, Sabine, Knopp, Tanja, Münzel, Thomas, Walter, Ulrich, Karbach, Susanne H., Wenzel, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813037/
https://www.ncbi.nlm.nih.gov/pubmed/29445199
http://dx.doi.org/10.1038/s41598-018-21273-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813037/
https://www.ncbi.nlm.nih.gov/pubmed/29445199
http://dx.doi.org/10.1038/s41598-018-21273-5

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