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Glycine receptor modulating antibody predicting treatable stiff-person spectrum disorders

BACKGROUND: Glycine receptor alpha-1 subunit (GlyRα1)-immunoglobulin G (IgG) is diagnostic of stiff-person syndrome (SPS) spectrum but has been reported detectable in other neurologic diseases for which significance is less certain. METHODS: To assess GlyRα1-IgGs as biomarkers of SPS spectrum among...

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Detalles Bibliográficos
Autores principales: Hinson, Shannon R., Lopez-Chiriboga, A. Sebastian, Bower, James H., Matsumoto, Joseph Y., Hassan, Anhar, Basal, Eati, Lennon, Vanda A., Pittock, Sean J., McKeon, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813079/
https://www.ncbi.nlm.nih.gov/pubmed/29464188
http://dx.doi.org/10.1212/NXI.0000000000000438