High-throughput and direct measurement of androgen levels using turbulent flow chromatography liquid chromatography-triple quadrupole mass spectrometry (TFC-LC-TQMS) to discover chemicals that modulate dihydrotestosterone production in human prostate cancer cells

OBJECTIVES: To develop a high-throughput screening system to measure the conversion of testosterone to dihydrotestosterone (DHT) in cultured human prostate cancer cells using turbulent flow chromatography liquid chromatography-triple quadrupole mass spectrometry (TFC-LC-TQMS). RESULTS: After optimiz...

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Detalles Bibliográficos
Autores principales: Kang, Kyungsu, Peng, Lei, Jung, Yu-Jin, Kim, Joo Yeon, Lee, Eun Ha, Lee, Hee Ju, Kim, Sang Min, Sung, Sang Hyun, Pan, Cheol-Ho, Choi, Yongsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813082/
https://www.ncbi.nlm.nih.gov/pubmed/29164416
http://dx.doi.org/10.1007/s10529-017-2480-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813082/
https://www.ncbi.nlm.nih.gov/pubmed/29164416
http://dx.doi.org/10.1007/s10529-017-2480-5

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