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Hydroxynitrile lyases from cyanogenic millipedes: molecular cloning, heterologous expression, and whole-cell biocatalysis for the production of (R)-mandelonitrile

Hydroxynitrile lyases (HNLs), which are key enzymes in cyanogenesis, catalyze the cleavage of cyanohydrins into carbonyl compounds and hydrogen cyanide. Since HNLs also catalyze the reverse reaction, they are used industrially for the asymmetric synthesis of cyanohydrins, which are valuable building...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Takuya, Nuylert, Aem, Ina, Atsutoshi, Tanabe, Tsutomu, Asano, Yasuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813103/
https://www.ncbi.nlm.nih.gov/pubmed/29445093
http://dx.doi.org/10.1038/s41598-018-20190-x