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Hydroxynitrile lyases from cyanogenic millipedes: molecular cloning, heterologous expression, and whole-cell biocatalysis for the production of (R)-mandelonitrile
Hydroxynitrile lyases (HNLs), which are key enzymes in cyanogenesis, catalyze the cleavage of cyanohydrins into carbonyl compounds and hydrogen cyanide. Since HNLs also catalyze the reverse reaction, they are used industrially for the asymmetric synthesis of cyanohydrins, which are valuable building...
Autores principales: | Yamaguchi, Takuya, Nuylert, Aem, Ina, Atsutoshi, Tanabe, Tsutomu, Asano, Yasuhisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813103/ https://www.ncbi.nlm.nih.gov/pubmed/29445093 http://dx.doi.org/10.1038/s41598-018-20190-x |
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