The mechanism of attenuation of epithelial‐mesenchymal transition by a phosphodiesterase 5 inhibitor via renal klotho expression

Phosphodiesterase‐5 (PDE‐5) inhibitors induces vasodilation in several organs by blocking cyclic GMP (guanosine monophosphate) degradation. However, the existence of alternative mechanism of action in case of an impaired nitric oxide (NO) system remains controversial. Previous studies suggested that...

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Detalles Bibliográficos
Autores principales: Han, Seung T, Kim, Jae S, Lee, Jun Y, Kim, Min K, Yoo, Jin S, Han, Byoung G, Choi, Seung O, Yang, Jae W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813144/
https://www.ncbi.nlm.nih.gov/pubmed/29029361
http://dx.doi.org/10.1111/1440-1681.12872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813144/
https://www.ncbi.nlm.nih.gov/pubmed/29029361
http://dx.doi.org/10.1111/1440-1681.12872

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