Cargando…

Expression of the FGFR2c mesenchymal splicing variant in human keratinocytes inhibits differentiation and promotes invasion

The altered isoform switching of the fibroblast growth factor receptor 2 (FGFR2) and aberrant expression of the mesenchymal FGFR2c isoform in epithelial cells is involved in cancer progression. We have recently described that the ectopic expression of FGFR2c in normal human keratinocytes induces epi...

Descripción completa

Detalles Bibliográficos
Autores principales: Ranieri, Danilo, Rosato, Benedetta, Nanni, Monica, Belleudi, Francesca, Torrisi, Maria Rosaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813158/
https://www.ncbi.nlm.nih.gov/pubmed/29068468
http://dx.doi.org/10.1002/mc.22754