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Thermal stabilization of the deglycating enzyme Amadoriase I by rational design

Amadoriases are a class of FAD-dependent enzymes that are found in fungi, yeast and bacteria and that are able to hydrolyze glycated amino acids, cleaving the sugar moiety from the amino acidic portion. So far, engineered Amadoriases have mostly found practical application in the measurement of the...

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Detalles Bibliográficos
Autores principales: Rigoldi, Federica, Donini, Stefano, Giacomina, Francesca, Sorana, Federico, Redaelli, Alberto, Bandiera, Tiziano, Parisini, Emilio, Gautieri, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813194/
https://www.ncbi.nlm.nih.gov/pubmed/29445091
http://dx.doi.org/10.1038/s41598-018-19991-x