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Characterization of the Conjugation Pattern in Large Polysaccharide–Protein Conjugates by NMR Spectroscopy

Carbohydrate‐based vaccines are among the safest and most effective vaccines and represent potent tools for prevention of life‐threatening bacterial infectious diseases, like meningitis and pneumonia. The chemical conjugation of a weak antigen to protein as a source of T‐cell epitopes generates a gl...

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Detalles Bibliográficos
Autores principales: Giuntini, Stefano, Balducci, Evita, Cerofolini, Linda, Ravera, Enrico, Fragai, Marco, Berti, Francesco, Luchinat, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813213/
https://www.ncbi.nlm.nih.gov/pubmed/29024352
http://dx.doi.org/10.1002/anie.201709274