The polypeptide biophysics of proline/alanine‐rich sequences (PAS): Recombinant biopolymers with PEG‐like properties

PAS polypeptides comprise long repetitive sequences of the small L‐amino acids proline, alanine and/or serine that were developed to expand the hydrodynamic volume of conjugated pharmaceuticals and prolong their plasma half‐life by retarding kidney filtration. Here, we have characterized the polymer...

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Detalles Bibliográficos
Autores principales: Breibeck, Joscha, Skerra, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813227/
https://www.ncbi.nlm.nih.gov/pubmed/29076532
http://dx.doi.org/10.1002/bip.23069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813227/
https://www.ncbi.nlm.nih.gov/pubmed/29076532
http://dx.doi.org/10.1002/bip.23069

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