Selective inhibition of TRPM2 channel by two novel synthesized ADPR analogues

Transient receptor potential melastatin‐2 (TRPM2) channel critical for monitoring internal body temperature is implicated in the pathological processes such as neurodegeneration. However, lacking selective and potent TRPM2 inhibitors impedes investigation and validation of the channel as a drug targ...

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Detalles Bibliográficos
Autores principales: Luo, Xiao, Li, Meng, Zhan, Kaiyu, Yang, Wei, Zhang, Lihe, Wang, KeWei, Yu, Peilin, Zhang, Liangren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813235/
https://www.ncbi.nlm.nih.gov/pubmed/29034580
http://dx.doi.org/10.1111/cbdd.13119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813235/
https://www.ncbi.nlm.nih.gov/pubmed/29034580
http://dx.doi.org/10.1111/cbdd.13119

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