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3D microfluidic liver cultures as a physiological preclinical tool for hepatitis B virus infection
With more than 240 million people infected, hepatitis B virus (HBV) is a major health concern. The inability to mimic the complexity of the liver using cell lines and regular primary human hepatocyte (PHH) cultures pose significant limitations for studying host/pathogen interactions. Here, we descri...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813240/ https://www.ncbi.nlm.nih.gov/pubmed/29445209 http://dx.doi.org/10.1038/s41467-018-02969-8 |