3D microfluidic liver cultures as a physiological preclinical tool for hepatitis B virus infection

With more than 240 million people infected, hepatitis B virus (HBV) is a major health concern. The inability to mimic the complexity of the liver using cell lines and regular primary human hepatocyte (PHH) cultures pose significant limitations for studying host/pathogen interactions. Here, we descri...

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Detalles Bibliográficos
Autores principales: Ortega-Prieto, A. M., Skelton, J. K., Wai, S. N., Large, E., Lussignol, M., Vizcay-Barrena, G., Hughes, D., Fleck, R. A., Thursz, M., Catanese, M. T., Dorner, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813240/
https://www.ncbi.nlm.nih.gov/pubmed/29445209
http://dx.doi.org/10.1038/s41467-018-02969-8

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