Pharmacokinetic-pharmacodynamic correlations in the development of ginger extract as an anticancer agent

Anticancer efficacy of ginger phenolics (GPs) has been demonstrated in various in vitro assays and xenograft mouse models. However, only sub-therapeutic plasma concentrations of GPs were detected in human and mouse pharmacokinetic (PK) studies. Intriguingly, a significant portion of GPs occurred as...

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Detalles Bibliográficos
Autores principales: Mukkavilli, Rao, Yang, Chunhua, Tanwar, Reenu Singh, Saxena, Roopali, Gundala, Sushma R., Zhang, Yingyi, Ghareeb, Ahmed, Floyd, Stephan D., Vangala, Subrahmanyam, Kuo, Wei-Wen, Rida, Padmashree C. G., Aneja, Ritu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813242/
https://www.ncbi.nlm.nih.gov/pubmed/29445099
http://dx.doi.org/10.1038/s41598-018-21125-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813242/
https://www.ncbi.nlm.nih.gov/pubmed/29445099
http://dx.doi.org/10.1038/s41598-018-21125-2

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