The RIG‐I‐like receptor LGP2 inhibits Dicer‐dependent processing of long double‐stranded RNA and blocks RNA interference in mammalian cells

In vertebrates, the presence of viral RNA in the cytosol is sensed by members of the RIG‐I‐like receptor (RLR) family, which signal to induce production of type I interferons (IFN). These key antiviral cytokines act in a paracrine and autocrine manner to induce hundreds of interferon‐stimulated gene...

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Detalles Bibliográficos
Autores principales: van der Veen, Annemarthe G, Maillard, Pierre V, Schmidt, Jan Marten, Lee, Sonia A, Deddouche‐Grass, Safia, Borg, Annabel, Kjær, Svend, Snijders, Ambrosius P, Reis e Sousa, Caetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813259/
https://www.ncbi.nlm.nih.gov/pubmed/29351913
http://dx.doi.org/10.15252/embj.201797479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813259/
https://www.ncbi.nlm.nih.gov/pubmed/29351913
http://dx.doi.org/10.15252/embj.201797479

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