Cargando…

ERAD‐dependent control of the Wnt secretory factor Evi

Active regulation of protein abundance is an essential strategy to modulate cellular signaling pathways. Within the Wnt signaling cascade, regulated degradation of β‐catenin by the ubiquitin‐proteasome system (UPS) affects the outcome of canonical Wnt signaling. Here, we found that abundance of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Glaeser, Kathrin, Urban, Manuela, Fenech, Emma, Voloshanenko, Oksana, Kranz, Dominique, Lari, Federica, Christianson, John C, Boutros, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813261/
https://www.ncbi.nlm.nih.gov/pubmed/29378775
http://dx.doi.org/10.15252/embj.201797311