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Library-to-Library Synthesis of Highly Substituted α-Aminomethyl Tetrazoles via Ugi Reaction

[Image: see text] α-Aminomethyl tetrazoles, recently made accessible by an Ugi multicomponent reaction (MCR), were shown to be excellent starting materials for a further Ugi MCR, yielding substituted N-methyl-2-(((1-methyl-1H-tetrazol-5-yl)methyl)amino)acetamides having four points of diversity in a...

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Detalles Bibliográficos
Autores principales: Patil, Pravin, Mishra, Bhupendra, Sheombarsing, Gitanjali, Kurpiewska, Katarzyna, Kalinowska-Tłuścik, Justyna, Dömling, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813278/
https://www.ncbi.nlm.nih.gov/pubmed/29215263
http://dx.doi.org/10.1021/acscombsci.7b00137