Hypoxia-induced the upregulation of stromal cell-derived factor 1 in fibroblast-like synoviocytes contributes to migration of monocytes into synovium tissue in rheumatoid arthritis

BACKGROUND: Rheumatoid arthritis (RA) is an auto-immune disease characterized by chronic inflammation of multiple joints. Hypoxia is a constant feature of synovial microenvironment in RA. Fibroblast-like synoviocytes (FLSs), which are potent effector cells in RA. It has been reported that large numb...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Ru, Yao, Yanhua, Wang, Panjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813381/
https://www.ncbi.nlm.nih.gov/pubmed/29456830
http://dx.doi.org/10.1186/s13578-018-0210-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813381/
https://www.ncbi.nlm.nih.gov/pubmed/29456830
http://dx.doi.org/10.1186/s13578-018-0210-x

Ejemplares similares