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Thiopurine S-methyltransferase activity in Nigerians: phenotypes and activity reference values

OBJECTIVES: This study assessed the activity of thiopurine S-methyltransferase (TPMT) in Nigerians with a view to providing data on susceptibility to thiopurine toxicity, and as well generate reference activity values for clinical use. RESULTS: TPMT activity, expressed as the amount of 6MMP in ng/mL...

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Detalles Bibliográficos
Autores principales: Adehin, Ayorinde, Bolaji, Oluseye O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813413/
https://www.ncbi.nlm.nih.gov/pubmed/29444714
http://dx.doi.org/10.1186/s13104-018-3237-5