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Extracellular ATP activates store-operated Ca(2+) entry in white adipocytes: functional evidence for STIM1 and ORAI1

In the present study, we have applied ratiometric measurements of intracellular Ca(2+) concentrations ([Ca(2+)](i)) to show that extracellularly applied ATP (adenosine triphosphate) (100 µM) stimulates store-operated Ca(2+) entry (SOCE) in 3T3-L1 adipocytes. ATP produced a rapid increase in [Ca(2+)]...

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Detalles Bibliográficos
Autores principales: El Hachmane, Mickaël F., Ermund, Anna, Brännmark, Cecilia, Olofsson, Charlotta S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813502/
https://www.ncbi.nlm.nih.gov/pubmed/29335300
http://dx.doi.org/10.1042/BCJ20170484