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Maternal high-fat diet associated with altered gene expression, DNA methylation, and obesity risk in mouse offspring

We investigated maternal obesity in inbred SM/J mice by assigning females to a high-fat diet or a low-fat diet at weaning, mating them to low-fat-fed males, cross-fostering the offspring to low-fat-fed SM/J nurses at birth, and weaning the offspring onto a high-fat or low-fat diet. A maternal high-f...

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Detalles Bibliográficos
Autores principales: Keleher, Madeline Rose, Zaidi, Rabab, Shah, Shyam, Oakley, M. Elsa, Pavlatos, Cassondra, El Idrissi, Samir, Xing, Xiaoyun, Li, Daofeng, Wang, Ting, Cheverud, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813940/
https://www.ncbi.nlm.nih.gov/pubmed/29447215
http://dx.doi.org/10.1371/journal.pone.0192606