The enzymatic processing of α-dystroglycan by MMP-2 is controlled by two anchoring sites distinct from the active site

Dystroglycan (DG) is a membrane receptor, belonging to the dystrophin-glycoprotein complex (DGC) and formed by two subunits, α-dystroglycan (α-DG) and β-dystroglycan (β -DG). The C-terminal domain of α-DG and the N-terminal extracellular domain of β -DG are connected, providing a link between the ex...

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Detalles Bibliográficos
Autores principales: Gioia, Magda, Fasciglione, Giovanni Francesco, Sbardella, Diego, Sciandra, Francesca, Casella, MariaLuisa, Camerini, Serena, Crescenzi, Marco, Gori, Alessandro, Tarantino, Umberto, Cozza, Paola, Brancaccio, Andrea, Coletta, Massimo, Bozzi, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813964/
https://www.ncbi.nlm.nih.gov/pubmed/29447293
http://dx.doi.org/10.1371/journal.pone.0192651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813964/
https://www.ncbi.nlm.nih.gov/pubmed/29447293
http://dx.doi.org/10.1371/journal.pone.0192651

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