Low apolipoprotein A-I levels in Friedreich’s ataxia and in frataxin-deficient cells: Implications for therapy

Friedreich’s ataxia (FA) is an autosomal recessive neurodegenerative disorder, which results primarily from reduced expression of the mitochondrial protein frataxin. FA has an estimated prevalence of one in 50,000 in the population, making it the most common hereditary ataxia. Paradoxically, mortali...

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Detalles Bibliográficos
Autores principales: Wang, QingQing, Guo, Lili, Strawser, Cassandra J., Hauser, Lauren A., Hwang, Wei-Ting, Snyder, Nathaniel W., Lynch, David R., Mesaros, Clementina, Blair, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813973/
https://www.ncbi.nlm.nih.gov/pubmed/29447225
http://dx.doi.org/10.1371/journal.pone.0192779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813973/
https://www.ncbi.nlm.nih.gov/pubmed/29447225
http://dx.doi.org/10.1371/journal.pone.0192779

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