Propofol induces a metabolic switch to glycolysis and cell death in a mitochondrial electron transport chain-dependent manner

The intravenous anesthetic propofol (2,6-diisopropylphenol) has been used for the induction and maintenance of anesthesia and sedation in critical patient care. However, the rare but severe complication propofol infusion syndrome (PRIS) can occur, especially in patients receiving high doses of propo...

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Detalles Bibliográficos
Autores principales: Sumi, Chisato, Okamoto, Akihisa, Tanaka, Hiromasa, Nishi, Kenichiro, Kusunoki, Munenori, Shoji, Tomohiro, Uba, Takeo, Matsuo, Yoshiyuki, Adachi, Takehiko, Hayashi, Jun-Ichi, Takenaga, Keizo, Hirota, Kiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813975/
https://www.ncbi.nlm.nih.gov/pubmed/29447230
http://dx.doi.org/10.1371/journal.pone.0192796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813975/
https://www.ncbi.nlm.nih.gov/pubmed/29447230
http://dx.doi.org/10.1371/journal.pone.0192796

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