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Notch signaling inhibitor DAPT provides protection against acute craniocerebral injury

Notch signaling pathway is involved in many physiological and pathological processes. The γ-secretase inhibitor DAPT inhibits Notch signaling pathway and promotes nerve regeneration after cerebral ischemia. However, neuroprotective effects of DAPT against acute craniocerebral injury remain unclear....

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Detalles Bibliográficos
Autores principales: Zhang, Hong-Mei, Liu, Pei, Jiang, Cheng, Jin, Xiao-Qing, Liu, Rui-Ning, Li, Shun-Qing, Zhao, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814062/
https://www.ncbi.nlm.nih.gov/pubmed/29447233
http://dx.doi.org/10.1371/journal.pone.0193037