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Notch signaling inhibitor DAPT provides protection against acute craniocerebral injury
Notch signaling pathway is involved in many physiological and pathological processes. The γ-secretase inhibitor DAPT inhibits Notch signaling pathway and promotes nerve regeneration after cerebral ischemia. However, neuroprotective effects of DAPT against acute craniocerebral injury remain unclear....
Autores principales: | Zhang, Hong-Mei, Liu, Pei, Jiang, Cheng, Jin, Xiao-Qing, Liu, Rui-Ning, Li, Shun-Qing, Zhao, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814062/ https://www.ncbi.nlm.nih.gov/pubmed/29447233 http://dx.doi.org/10.1371/journal.pone.0193037 |
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